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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d2fd4f66aee604986cbf408c0b3e51a4f4474495703a2f9664ad0e7db78d75' 
  AND token = 'N6sgAA7t+sqmzcGK5PcjxBjprM9xQue4tlfvn3KTxR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}