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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357937d9a997fa3eb757f721244abea72a3af4ee119edb31258708ff6b8f8bbf' 
  AND token = 'WKMB01iG0T0pDw64zB/viB7BCYxfrjpCt3A3F1AAmp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}