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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '731dc7ef352ad1c37d571853f7c6cb28984170ba3cca82ded160de5d9462cfb2' 
  AND token = 'r26vlNiMhNXts1gHfq+s6URU3LUvLJyYcq5zcaLe3cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}