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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290ed671e9c17473f48ccf37c2fa369a14830689b3bf8b8823e0e8872f7663f4' 
  AND token = 'sjEf+QA8UdEO6ZbGllAvQPx+eO2rdwRRfN+gxiQePT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}