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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf6a6f412f85191b2c942a49c82eb0b9f516a179b629fd09195b44cec058eb46' 
  AND token = 'Z9bMKcxbRswJXq2scfLqwwjvBCoo+BNE5YjCi+kzpnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}