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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066bade5c3810e342f53ef11286c9da218a30c7951c099ba6ac497f38fd480da' 
  AND token = 'nzcwVQ6qFdQIxJ+UtaVPppXAFou+7oEzfv+uNsREIsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}