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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eba46b017091197fac68a725ccceb37f73d2494a502d88d33d9e1ac4cbb31a6' 
  AND token = 'G56ST0eVJJiCTetBW7b+mx2WwX0pf5pfjCcF1wXbzkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}