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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249f96f7b308846188639a5e38e528ffb5a109ffcc1fa487ab91b9b49ee5c563' 
  AND token = 'yhTEbob20dF97gX8cDj1gc8vaGSMjgoHeqNDVTXPUmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}