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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0da54f927aa8127135690082fd82b56f5f7c227348f4f7d8c3b959e8adb159e' 
  AND token = 'v6t/SdP09YtaLjQvw45Vu2L/tfXiwYC2P4HtHtYRPRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}