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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101e91ece053f906669c008fbd7704ecf2b4bf801d3b672e65390c290bb26c18' 
  AND token = 'Pk+H8lG6hHZiIHJvO0xLADHHW+gUCGwima1tFW+LQkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}