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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd7e356eff97279dbfa0b3c83071c989960307af1f1dd3ded4de4f0e1562e4b' 
  AND token = 'sReIne0NuJIJ72jPD0DAdgW2/sDDj4zHNCKAJ27fTEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}