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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e272f5a46f97f2987298391a886bacd3fb5feab94d0ffc00485fc35eff9d3cc4' 
  AND token = 'Z/sbW/+NsxrVTdu2Mztazd78AxUoL0je3AnjpaPPwB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}