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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00f0d1d5812422f387eff6f619233f82522178a632701049918777754dfe780' 
  AND token = 'wf5bXHuMfe3nFQYXlcRIEddRKKvr6x/3aU7akC6LvuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}