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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27377176d1aa96e1f3f8b3957ce3b77a420e9ef46a019b0b7c342dc5645185ec' 
  AND token = 'Qze2MP+s4vBeFIpnrFCfgxns2MNSg66GxRQfLLm8KsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}