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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455e28c76b5ce6382b40651585a3c98d80618e3eb2cfc8072e46ab37ad19a9d6' 
  AND token = 'Rr4FT1ml1VHkDrXpkv+rcZAwV7TmD+RWuQAfnR1pRpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}