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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3c99597ef389f2021b25b3254cab084f31dfd50ac42875c4a165f9a5da0cf5' 
  AND token = 'mUc9JU5gJix0GdvmztAuMW2yh82ygE9lFGFaxyXp7bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}