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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f05d8214cadc90e21fbe4a67c469039902742baa854d47b66084cba077f6cd1' 
  AND token = 'GGYYV9+RIjb8DPTaduQdqHAuWSmADHQZ6RfHheGq7Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}