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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61d2e6d5fa25b65782d6f69b5dfa0a25d431e8a6e550e89e3f2a33aee9c40d8' 
  AND token = '5/PSTM91uF19HrmUytO72dm4Zd4Owb+AT7jjRAP9QJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}