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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef5e96423d124ff4118c000c6f51b91621ebd765f3e1387e0725b272bb652e3' 
  AND token = 'tqIauF4jU8+hRaRYmsINzPF85QdQRoxaKQmhTw74AeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}