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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ba474f5b8b2a8e4078b4a69beffb9c90e25b3fa5da71f5225d7577a1e59edd' 
  AND token = 'UwHZB6PWVjSs52OI9LJBhc85sDpL+vPsC2kumpN3W1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}