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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27853f77be843dd92feeaaa701704a3cb13acc97f6cdcaceafabac1972d0a07d' 
  AND token = 'fjw8QTgoKGPKEdAR0s+9IhChXWNLC3KB4qJpdLi/qQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}