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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d80fd1451e4588db0a5f5c9fb8a9f6b32d0aa2043956b7800a4bf8e972e4144' 
  AND token = 'VbYjh2PArS50KjwO4XEx+e0UXDHf4dQI6sOpEUkyApc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}