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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f662cc4bc94d19305ef0edb2aaf1c40459cd81f6c561395d93a66cf39ce305' 
  AND token = 'sh1P5m2EbTEKao0+go0xzlmQW3oDOcdO9NIeigV60vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}