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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe65c48d66bf397e2f01c0f281bce7f3cccffe971fc7258d0da2b72615c1c3c' 
  AND token = 'ig+3Bynvhu0QHU9scqDqJ6eqgrRL8TNrZX2dJSH0rwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}