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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45f599ce6c54402e56b0747a509fd0e829fda6a15bf6cb0d9d1538532130b5e' 
  AND token = 'h76Fj6HXm0ASpSTYSKnB+aqcTFbFCHDnEXPJaDgt2NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}