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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb51a96ced0859ee81f66b6fea33eee71da1d6e1348a546bf8f01efe77b80f49' 
  AND token = 'rQIXUSB2u4JB7nn0EOC5mvyz1SgJbLFSaCNtXrWPm5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}