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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3e9680253395e9ef195c62964b1331aa9bead60b8811dfda73008f6c125c9d' 
  AND token = 'hf3rXeGeS71B6WVarBX8qxvpqllPxMOyRxK7bTOT2bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}