SELECT 
  variant_id, 
  yml2_unit 
FROM 
  cscart_product_feature_variant_descriptions 
WHERE 
  variant_id IN (
    '1661', '597', '1', '441', '1634', '429', 
    '433', '513', '1805', '1667', '1662', 
    '1633', '1619', '460', '447', '122', 
    '121', '440', '127', '439', '1349', 
    '362', '438', '149', '246', '120', 
    '1668', '1804', '430', '448', '1620', 
    '442', '1663', '1623', '1635', '1630', 
    '1664', '146', '431', '446', '59', 
    '147', '98', '280', '1637', '1627', 
    '1629', '170', '1628', '165'
  ) 
  AND lang_code = 'ru'

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "35.01"
    },
    "table": {
      "table_name": "cscart_product_feature_variant_descriptions",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY"
      ],
      "key": "PRIMARY",
      "used_key_parts": [
        "variant_id",
        "lang_code"
      ],
      "key_length": "9",
      "rows_examined_per_scan": 50,
      "rows_produced_per_join": 50,
      "filtered": "100.00",
      "index_condition": "((`test_uchur_k`.`cscart_product_feature_variant_descriptions`.`variant_id` in ('1661','597','1','441','1634','429','433','513','1805','1667','1662','1633','1619','460','447','122','121','440','127','439','1349','362','438','149','246','120','1668','1804','430','448','1620','442','1663','1623','1635','1630','1664','146','431','446','59','147','98','280','1637','1627','1629','170','1628','165')) and (`test_uchur_k`.`cscart_product_feature_variant_descriptions`.`lang_code` = 'ru'))",
      "cost_info": {
        "read_cost": "30.01",
        "eval_cost": "5.00",
        "prefix_cost": "35.01",
        "data_read_per_join": "155K"
      },
      "used_columns": [
        "variant_id",
        "lang_code",
        "yml2_unit"
      ]
    }
  }
}

Result

variant_id yml2_unit
1
59
98
120
121
122
127
146
147
149
165
170
246
280
362
429
430
431
433
438
439
440
441
442
446
447
448
460
513
597
1349
1619
1620
1623
1627
1628
1629
1630
1633
1634
1635
1637
1661
1662
1663
1664
1667
1668
1804
1805