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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2c4e0043c626a69915f7cdb90ecfc59d1f15b1f3de9757878b7078aa83f7a3' 
  AND token = 'M3w28wq7zGqZgWaf99LMVcX8wcJIWRpkG71/tgC9bz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}