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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78aa04b9ff033592d90b15b8914814c7994dfb1a3eedc02678b45216fa6a641d' 
  AND token = 'H2xrXW4RiBJDvTnAK2ej173guKo7sOKfWTXyWWBJU2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}