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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f25ea6396e1e4f5a8c412b92e2fca33ba0935ea3213eae4b65786c0c9943cb2' 
  AND token = 'HvgrCHQ+mdKgdPbPmr+pIKJHUin3UgD0eEocrUgQbGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}