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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cf249348c490d597a7f9445f2dfc1199c05c9eefec19a06218e2cf1d10a59e' 
  AND token = '9h0dClWeXbkR6elpcJtALTSGPcD9iTBMnlUxgFp5VQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}