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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa323e7e9874a26ff3507317e1ae0ee9ae97178f4f330f09688165ff8699111' 
  AND token = 'XR1tvZEYq2tpxNYNuCvdX/r1pc4cG7Pbw4cVZGI0rHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}