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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7bdab7f2e45138733fa05ee7cfd9d8012400a43e0fe2cd21125d4aec18b49b' 
  AND token = 'jo1spYYloGaa8eI58h/65wB3tbOmEd2sIbSTkIvPYLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}