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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d45497f3e8a6ae67a3741aa88133a3961b58153f05d0cf73cabb1fdcd0193b3' 
  AND token = 'CcegDvdLtN3A+7TOfv0IiEW5lGUJDIEll891QYkvTEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}