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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91360fa78187197e6d3524249fecd964849b61ed54551dd7a49b01104608776b' 
  AND token = 'O2iyiJfiRJvqcDn0vgn4NRdGcBa9GynUQS+Dvwv6zc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}