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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04275f2e7f43f6de115f5cf475507e1251f6c46fe0f6cbefea01c35ad7b4788' 
  AND token = 'qsAfGAPYgnWrMvJgbKdEBzE52nG7jit4f3Wl3ADVnyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}