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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4291ec037f4372eebc84c8509aa9f5710bcc1976928707acaf9171f41442923' 
  AND token = 'bPh7tpBjZrh6Ep7iJlcAoMhFhGLOdwYJmx+BitSi7Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}