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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a144a607806b9867a84345d412d6b580e7154d8bcb3b75954c17b7999da6a8c3' 
  AND token = 'qNdPBcEWOswKNANDmjXggiMybYbEw1Hy7w5U7njQ/rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}