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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b68529b775b977ee2997f9641a2cf5e14b90c1fa6e46e72782170a47e4fe882' 
  AND token = 'byahfR/pJhmrn2YfFR0miscGa3nzkqbLfpBRXhdCGJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}