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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33aaee772293ab23469b351933bd36c7d32a7ab10cb677189ee09eabeff720c3' 
  AND token = 'rEoFHK9KiBY2HFybVoJwgMkdHr6YClSGAJTQ59B8DGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}