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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5262a429f9294caa83f1e9a20c6f4221d2e21d14ce45c819808cb585fb38341' 
  AND token = 'qLqBcTtJ+JkKNZSvOqe7HHQ5XiHYW/NLW/eESYRMx1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}