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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4db66b8cf28b08b06866c91a9aa75fd75ece1a1c1104f67cc7c4ecc0f01b4aa' 
  AND token = 'f0YtGXKXseTy1CwmGu/vD7v0xrqdy4zfpxe0DrLNJOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}