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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e452989127908ff1f50c82af3466a2d6cca523e2c599a14a20e4a2a3ced21d6c' 
  AND token = 'PwfnyBXHQqFgWgPdxHTrXk3dI0Zyg+m60SCNOP4rvSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}