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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1e2fd2964a4c63cd72105113c223bb9729d470201885689f97e8afa5ae25c2' 
  AND token = '7+QpU1a8nRhYuQgZuodnjw+FRBdtOy+u08PYU+7RbmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}