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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b7fa77f7988da3f524d4cae1f0bd3c1bfed11d6bd0a37e0ce21c23df395330' 
  AND token = 'joCLCvCBf4p7hy0yj5T2e2D+vTCISc/jfPD9RgpLOwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}