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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffc22f50ca902ccbefd80c4cb622b396014fbd7d0a37f28b997b057d9e3e58a' 
  AND token = 'STJzx7TXL8OpHT7yJ6H6m2HArZtOg836TU/AvAESRW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}