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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad31b100a27797b39381a20f805794dd18a2aad53769212189d339c37a4218e' 
  AND token = '4cT+5w6lk2vuTxvTOd/cK+0OWC24EVK7TCe0GMfc5do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}