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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b31e2ec4f72f7ae1e847a43d3f3da3450708f58eda31a7a39036f83408cbd67' 
  AND token = 'DXyZVM8agMbiOaXnlL/Ii6wvQ48MwoyFgtjpzuzzWtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}