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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6c1f7f30988a365a35020cd63c0b5d0524ceec64756e08a632d393165867a2' 
  AND token = '/K0htFNKm6XE8S+OoFUPKDSFsfa/xF3FHsePNIiP5m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}